Principal Investigator
Group Leader
Ragon Institute of Mass General, MIT, and Harvard
Assistant Professor
MIT Department of Biological Engineering
Associate Member
Broad Institute
(617) 258 7641
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The Bryson lab is working to determine how cells of the immune system control and eliminate one of the world’s most deadly pathogens, Mycobacterium tuberculosis (Mtb).
How Mycobacterium tuberculosis is controlled by humans remains a poorly understood process. To address this knowledge gap, our research group combines approaches in microbiology, immunology, and bioengineering to understand and manipulate the complexity of phagocyte state and function in the lung. Paired with these cellular questions, our group develops novel tools to query and perturb the phagosome which we hypothesize contributes to effective Mtb control.
Dr. Bryson received a BS in Mechanical Engineering and PhD in Biological Engineering from MIT. He pursued postdoctoral training at the Harvard TH Chan School of Public Health with Sarah Fortune, where he became fascinated by the complexity of interactions between Mtb and the host. He joined the MIT faculty in 2018 and was promoted to Associate Professor Without Tenure in 2022.
Itoh, C. Y. et al.
bioRxiv 2020.09.29.318352 (2020) doi:10.1101/2020.09.29.318352
Hie, B. et al.
Annu. Rev. Biomed. Data Sci. 3, 339–364 (2020)
Peters, J. M., Blainey, P. C. & Bryson, B. D.
bioRxiv 2020.08.06.240424 (2020) doi:10.1101/2020.08.06.240424
Gideon, H. P. et al.
bioRxiv 2020.10.24.352492 (2020) doi:10.1101/2020.10.24.352492
Hie, B., Bryson, B. D. & Berger, B.
Cell Syst. (2020) doi:10.1016/j.cels.2020.09.007
Ma, F. et al.
bioRxiv 2020.12.01.406819 (2020) doi:10.1101/2020.12.01.406819
Bryson, B. D.
mSphere 6, (2021)
Hie, B., Zhong, E. D., Berger, B. & Bryson, B.
Science 371, 284–288 (2021)
Akeem Akilimali
Postdoctoral Fellow
Ben Allsup
Graduate Student
Jinjin Chen
Graduate Student
Diana Gong
Graduate Student
Cal Gunnarson
Graduate Student
Jasmin Joseph-Chazan
Graduate Student
Owen Leddy
Graduate Student
Bianca Lepe
Graduate Student
Amanda Mei
Undergraduate Student
Carlos Mercado-Lara
Undergraduate Student
Iris Abrahantes Morales
Research Technician I
Sharon Opara-Ndudu
Undergraduate Student
Ceili Peng
Graduate Student
Josh Peters
Graduate Student
Sydney Solomon
Graduate Student
Kelly Xu
Undergraduate Student
Christine Zheng
Graduate Student
Our people are our greatest asset. We are committed to creating a supportive and inclusive environment that is welcoming for all.
The Ragon’s faculty includes many of the world’s most creative scientists, engineers, and clinicians.
The Ragon’s research creates knowledge from our collaborative, cross-disciplinary approach, breaking down the silos of academia.